Single Cell Analysis of the Tumor Microenvironment

Posted By: Kariena-10x, on Mar 9, 2018 at 12:54 PM
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A critical component of personalized cancer treatments is understanding tumor heterogeneity, and in particular, understanding the complex interactions between malignant, stromal and infiltrating lymphocyte cell types within the tumor microenvironment (TME). The Chromium Single Cell Immune Profiling Solution provides a comprehensive approach to simultaneously examine the cellular context of the adaptive immune response and the immune repertoires of hundreds to millions of T and B cells on a cell-by-cell basis. In this workshop, 10x-perts Sarah Taylor and Stéphane Boutet will discuss their work utilizing the immune profiling solution to explore cellular heterogeneity and the adaptive immune phenotype in the tumor microenvironments of a colorectal cancer (CRC) tumor and a squamous cell non-small cell lung carcinoma (NSCLC).


In this workshop, our 10x-perts will cover:

  • Challenges understanding the tumor microenvironment
  • Factors to consider for tumor sample preparation
  • Library preparation for gene expression and immune repertoire from the same single cells
  • Live demo of data analysis in Loupe Cell and Loupe V(D)J Browsers


The workshop will begin with presentations by Dr. Taylor and Dr. Boutet followed by an open Q&A session.


Register for the 10x-pert Workshop →


For a preview, you can read about the results of these tumor profiling studies in our new application note.


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