Welcome to the 10x Blog

From tips and tricks to 10x news, our blog is here to help you learn about all things 10x. Let us know what topics you would like to see in the Community Suggestions forum.

November is National Diabetes Month, so we are highlighting some important diabetes research published this year and how 10x Genomics technology played a part in these discoveries.
Researchers from Vanderbilt University recently used single cell immune sequencing to identify a new panel of broadly neutralizing antibodies against HIV. Members of the research team, including graduate student Ian Setliff from the lab of Dr. Ivelin Georgiev, will discuss their discoveries in a 10x Genomics webinar, hosted by GEN, on November 14, 2019. 
With the Visium Spatial Gene Expression Solution, you can measure and map gene expression in the same tissue section, without the need for target pre-selection. Explore the spatial barcoding technology behind the solution. 
Read our VP, Global Support and Sales Operations’ letter regarding a Product Advisory for the Single Cell ATAC Solution.
Single cell gene expression studies can reveal previously undiscovered cell populations. See how researchers are using solutions from 10x Genomics to uncover rare and unexpected cell types in multiple tissues, including the lung, kidney, colon, and liver.
The Visium Solution creates a high-resolution map of gene expression in intact tissue sections without the need for target pre-selection. Learn how to prepare your lab for this new technology, and analyze spatial gene expression data, in our two upcoming webinars: Getting Started with the Visium Spatial Gene Expression Solution, October 29, 2019. And, Exploring New Frontiers - Analyzing and Visualizing Visium Gene Expression Data, November 19, 2019. 
Scientists from the Department of Translational Genomics at the Keck School of Medicine, USC used the Chromium Single Cell CNV Solution to revisit a well-studied melanoma cell line, COLO829. Previous attempts to resolve the heterogeneity of this cell line using multiple bulk methods were considered inconclusive due to the “averaging” nature of these methods. Now, using low coverage single cell copy number profiling, researchers believe they have uncovered four unique clones.
Spatial gene expression profiling can elucidate the underlying cellular and molecular mechanisms of normal neural development and disease. What else can this method do to advance neuroscience research? Find out at the 49th Annual Meeting of the Society for Neuroscience, in Chicago, IL.
How will single cell sequencing technologies shape the future of neuroscience research? Find answers, and check out 10x Genomics, at the 49th Annual Meeting of the Society for Neuroscience in Chicago, IL. 
In this guest blog post, Kasandra Burgos PhD, a 10x Genomics Science & Technology Advisor, shares her fascination with neuroscience. The mysteries of the mind intrigued Kasandra long before she started her career here, and now she’s excited to help customers understand the value of applying 10x Genomics assays to address questions in the field of neuroscience.
“We always had cancer in mind…” Read on to learn about the original vision of the 10x Genomics team to accelerate cancer research, and review five oncology papers authored by 10x Genomics customers, published this summer.
In a recent 10x webinar, Dr. Rahul Satija answered some of your questions about how to use Seurat v3 to harmonize single cell sequencing data across technologies and modalities.  
What are the cellular and molecular changes driving pathogenesis of autism spectrum disorder and multiple sclerosis? Find out how 10x Genomics customers use single cell and single nucleus gene expression profiling to approach these questions in two high profile neuroscience publications. 
Maniatis et al. used spatial transcriptomics to define changes in gene expression at different stages of ALS progression. Learn more at the Cell Symposia: Neuro-Immune Axis, starting September 22 in Long Beach, or watch Silas Maniatis in his upcoming webinar on October 8! 
Congratulations to Dr. Christoph Kuppe, a physician-scientist in the laboratory of Rafael Kramann (www.kramannlab.com) at Germany’s RWTH Aachen University, for winning the Visium Spatial Gene Expression Scientific Challenge. For his proposal to map human myocardial infarction, he has won a complete spatial gene expression experiment, including tissue preparation and data analysis, performed by members of the R&D team at 10x Genomics headquarters.
10x Genomics highlights two publications from scientists in the APAC region who are using single cell genomics tools to interrogate biological systems at previously inaccessible resolution and scale. 
In a recent webinar, Dr. Rahul Satija demonstrated the newest version of the single cell analysis toolkit, Seurat v3, with new and improved capabilities for integrating single cell sequencing data across technologies.
In this LabTools webinar, hosted by The Scientist, Dr. Jill Herschleb will explore critical sample prep decisions and considerations for assay design and optimization.
10x Genomics is inviting researchers to share innovative ideas for Spatial Gene Expression experiments for a chance to win a project performed by 10x Genomics (sample prep, library prep, sequencing, and data analysis). Plus, the winner will get access to the new product prior to the general public!  
Read our CEO and co-founder's letter to customers on the recent developments in the litigation campaign launched by Bio-Rad against 10x.
  Learn about analyzing and visualizing single cell ATAC-seq data (Assay for Transposase-Accessible Chromatin using sequencing)
  In May, 10x Genomics traveled to Tokyo to attend the EMBO Single Cell Biology Workshop and the Human Cell Atlas (HCA) General Assembly Meeting to learn all about recent scientific breakthroughs in single cell biology.
10x Genomics has partnered with GENEWIZ to sponsor the Single Cell Genomes Scientific Challenge. We want to hear how you can use our single cell DNA solution to study genomic heterogeneity and advance your research. Share your innovative ideas in a 300 word proposal before June 30th for the chance to win a single cell DNA project.
Each June, the Alzheimer’s Association® sponsors Alzheimer’s & Brain Awareness Month — an opportunity to hold a conversation about the brain and share the fact that Alzheimer’s disease and other dementias are a major public health issue.
Hear first-hand from 10x Genomics scientists about the recent advancements in immunological research that allow the integration of simultaneous cellular read-outs to provide comprehensive characterization of immune cells.
From African wild dogs to Hawaiian monk seals, from beluga whales to Northern sea otters, these mammals all share one thing—a connection to 10x Genomics. In honor of Earth Day 2019, we want to share how our technology is playing a role in important conservation research involving these diverse creatures.
To celebrate International Women’s Day, we’ve put together a playlist of some fierce women in science talking about topics ranging from immunotherapy to the microbiome to mapping the maternal-fetal interface on a single cell level.
Our bodies and the world around us teem with billions of invisible microbes. Join us for a webinar on February 13th to learn about a metagenomic assembly method, developed by Dr. Ami Bhatt and her team at Stanford University, which promises to help define these complex microbial communities and shed light on the mechanisms by which they influence health and disease.