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Single-cell RNA-seq enables researchers to examine gene expression on a cell-by-cell basis providing insights into the function and regulation of complex biological systems.  In our recent 10x-pert Workshop, R&D scientists discussed single-cell RNA-seq data analysis tools, including Cell Ranger™ analysis pipelines, and performed a live demo of Loupe™ Cell Browser for data visualization.
A recent PNAS publication from the laboratory of Dennis Lo applied the use of the 10x Genomics’ Chromium™ Single Cell 3’ Solution to comprehensively characterize the transcriptomic heterogeneity of the human placenta—an approach that served as confirmation for the non-invasive identification of cellular dysfunction during gestational complications such as preeclampsia.
We recently hosted our first live, online 10x-pert Workshop featuring single-cell sample prep topics.  Two of our R&D scientists gave a presentation detailing general do’s and don’ts followed by a closer look at two of our demonstrated protocols for preparing nuclei for single-cell RNA-seq and removing dead cells.
New to 10x or need a refresher?  No problem.  Check out our new Chromium™ Single Cell 3’ training video series. Learn more about GemCode™ technology, single cell sample prep, data analysis and more.
In a recent publication, researchers at the University of Hong Kong used 10x Linked-Reads in the prenatal identification of single gene disorders.