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read duplication percent

Posted By: gdaverdin, on Oct 19, 2017 at 3:19 AM

Hi there,

I would like to know if someone could help me to understand a bit more the read duplication. It seems that the percentage of read duplication is pretty high in my dataset and I was wondering why that could be? Does anyone has an answer or maybe a link to a post that could help me here?

Thanks a lot,

 

My data:

-   46.06  %  ==> fraction of reads that are duplicates

-   34.12  %  ==> nonduplicate and phased reads; ideal 45-50